Ramadan and diabetes: a collaborative approach to fasting

Dr Salim Parker gives a collaborative approach to Ramadan fasting.


One of the five pillars of Islam

Fasting from dawn (the meal in the morning is called Suhoor) to dusk (Iftaar) during the Muslim month of Ramadan is one of the five pillars of Islam. The Quran specifically instructs all mature and healthy Muslims that: “Oh you who believe! Fasting is prescribed to you as it was prescribed to those before you so that you may attain self-restraint.

Most Muslims start fasting from a very young age. Even though, it’s only obligatory when puberty is attained and it is a religious, social and community in most societies. The Islam religion follows the lunar calendar and Ramadan occurs 10 days earlier each successive year. This year (2019) it will be nearly the whole of May.

The sick are allowed to postpone the fast and may even be exempted from it, as stated in the Quran: “Whoever witnesses the month (of Ramadan) then he/she should fast. But, if any of you is ill or travelling – then he or she is exempted from fasting.”

Despite this concession many sick Muslims will fast despite learned religious scholars and medical professionals advising them not to. This applies equally to people living with diabetes and this article outlines some guidelines as to how to approach diabetics intending to fast.

Benefits of fasting

It’s known that there are several potential benefits of fasting during Ramadan. Feelings of compassion for the less fortunate and underprivileged are evoked in Muslims who fast. Though the hunger and thirst senses are heightened, the natural sense to eat or drink is controlled. This leads to a sense of having willpower and to be in control of the senses.

The long-term ideal is for Muslims to ultimately be able to resist daily unnecessary and potentially harmful forms of food as urged by the Quran to: “Eat of what is lawful and wholesome on the earth,’ and ‘And He (God) enforced the balance. That you exceed not the bounds; but observe the balance strictly and fall not short thereof.”

Fasting also offers a time to ‘cleanse’ the body and the soul. The person fasting is encouraged to develop a greater sense of humility, spirituality, and community involvement.

There are also indications of physiological benefits of fasting. Some studies indicate that intermittent fasting limits energy intake. This promotes weight loss in obese individuals, which could be cardio-protective. Insulin sensitivity is also increased.

A holistic approach needed

Currently, of the 366 million humans on earth living with diabetes, more than 50 million are Muslim. In 2015, diabetes was the leading cause of death amongst South African females, and the sixth most frequent one amongst males. Diabetes was the second leading cause of death overall in South Africa after tuberculosis that year.

Many South African Muslims living with diabetes will fast irrespective of their health status. It’s important that there should be synergy between the healthcare professionals, the Islamic scholars and the Muslims living with diabetes who want to fast. Several factors need to be considered:

  • Age of the person
  • Medications used
  • Insulin dependency or not
  • Co-morbidities
  • Recent complications
  • Whether living alone or not
  • Easy access to a glucometer
  • Social support

Lifestyle management

All Muslims living with diabetes should ideally have a pre-Ramadan consultation beforehand with their healthcare practitioner. Fasting and the management of lifestyle conditions go hand in hand and a holistic approach should be adopted.

Dietary intervention is essential and the inclusion of more fibre, complex carbohydrates, vegetables, legumes should be encouraged, as should sparing salt use.

There is increasing evidence that dates, a staple food type during Ramadan, may have beneficial effects on glucose and cholesterol levels during Ramadan and may lead to a decrease in cardiovascular risk factors. Dates, consumes in moderation, are rich in fibre and is high in fructose, which has a lower glycaemic index than sugar.

It’s known that not having breakfast, in the normal population, increases the possibility of being overweight by a factor of five, and increases the chance of developing diabetes. The consumption of the pre-dawn meal is hence paramount. Stopping smoking and optimising of medication and co-morbid conditions should be discussed as well.

Maintaining some form of exercise, such as the optional nightly Ramadan prayers (if possible and depending on level of fitness), is part of lifestyle maintenance.

Complications associated with fasting

Hypoglycaemia

Hypoglycaemia is the concern of most doctors and patients when fasting is contemplated by the Muslim living with diabetes. Several patients, especially the elderly, are not always aware when their glucose levels drop. In one study, 24 out of 29 subjects were not aware that their glucose levels were low.

Different patients will have different signs and symptoms at different levels, with a glucose level below 4 mm/L being dangerous in most instances. Signs are often subtle, such as slight inattentiveness, and may not be easily be picked up by household members. The easy availability of glucometers is paramount in all circumstances and it should be emphasised that checking the levels (finger prick test) does NOT invalidate the fast. If levels are low, the fast should be broken immediately with the religious edict that life and health are MORE important than obligations emphasised.

Hyperglycaemia

Ramadan, contrary to its intention, is associated with caloric excess. An abundance of savouries, pastries and desserts is the norm and people living with diabetes consume as much as others. Hyperglycaemia can thus occur and at times is difficult to distinguish from hypoglycaemia, based on signs and symptoms alone.

The availability of glucometers is thus again important. Patients often fear hypoglycaemia and reduce, or even stop, their medication on their own. Coupled with the dietary excess, the chances of hyperglycaemia are increased and in some countries, such as Pakistan, more cases of hyperglycaemia than hypoglycaemia are seen during Ramadan.

Dehydration

Dehydration, especially if the diabetes is poorly controlled, is a possible complication of fasting during Ramadan. Polyuria (production of abnormally large volumes of dilute urine) and a reluctance to consume too much fluids at night (to avoid urinating) increases the possibility and the development of pre-renal failure, and thrombosis may have to be considered.

Risk categories1 

Category 1: Very High Risk

This include patients with one or more of the following:

  • Severe hypoglycaemia within the three months prior to Ramadan.
  • Diabetic ketoacidosis (DKA) within the three months prior to Ramadan.
  • Hyperosmolar hyperglycaemic coma within the three months prior to Ramadan.
  • History of recurrent hypoglycaemia.
  • History of hypoglycaemia unawareness.
  • Poorly controlled Type1 diabetes mellitus (T1DM).
  • Acute illness.
  • Pregnancy in pre-existing diabetes, or gestational diabetes (GDM) treated with insulin or sulphonylureas.
  • Chronic dialysis or advanced kidney disease.
  • Advanced macrovascular complications.
  • Old age with ill health.

Patients in this category MUST NOT FAST. If they insist on fasting, close monitoring and counselling is essential, with specific instructions given on when they MUST break their fast if necessary. They must be informed that they are putting their health and life at risk.

Category 2: High Risk

In this category are patients with one or more of:

  • T2DM with sustained poor glycaemic control.
  • Well-controlled T1DM.
  • Well-controlled T2DM on MDI or mixed insulin.
  • Pregnant T2DM or GDM controlled by diet only or metformin.
  • Chronic kidney disease stage 3.
  • Stable macrovascular complications.
  • Patients with comorbid conditions that present additional factors.
  • People with diabetes performing intense physical labour.
  • Treatment with drugs that my affect cognitive function.

Patients in this category SHOULD NOT FAST. If they insist on fasting they should also be closely monitored.

Category 3: Moderate/low risk

The following fall in this category:

  • Lifestyle therapy
  • Metformin
  • Acarbose
  • Thiazolidinediones
  • Second-generation Sus
  • incretin-based therapy
  • SGLT2 inhibitors
  • Basal insulin

These patients should be able to fast with sound advice being given first.

Medication adjustment

Each person living with diabetes will have unique circumstances and should be counselled individually. Explaining the risks and symptoms of hypoglycaemia and what appropriate actions to take must be emphasised.

Patients on medication need to be advised to change their dosages to accommodate the daytime fast. Some general guidelines are given below. But, again it must be emphasised that each Muslim who intends fasting must have advice tailored to their unique situation.

Metformin

Metformin has a low-risk of causing hypoglycaemia and generally no dose adjustment is needed. Some authorities advise taking two thirds of the total daily dose with the evening meal, with one third taken with the morning meal. The once-a-day formulation should be taken at the usual dose in the evening.

Sulphonylureas (SU)

The first-generation SUs had a high propensity of causing hypoglycaemia and should be avoided. The second-generation SUs are much safer. The general rule for stable patients living with diabetes is to take half the morning dose and the normal evening dose.

The other option is to switch evening and morning doses and reduce the morning dose. The once-a-day formulation should be taken in the evening, instead of the morning with a halving of the dose for the first few days. The dose can then be adjusted as needed.

Insulin

The dose of basal insulin or once a day premix should initially be decreased by 20% and given in the evening. When basal insulin is given twice a day, the morning dose should be given in the evenings with half the evening dose given in the morning. The same applies to premixes given twice a day. Insulin that is used three times a day should have the midday dose omitted and the morning dose halved. The dosages can then be adjusted as needed.

Other diabetic medications

These generally do not need dose adjustments. Once daily doses should preferably be taken in the evening.

Conclusion

Ramadan is an ideal time for people living with diabetes to implement lifestyle changes that would be in accordance with their religion and improve their health as well as their diabetes control.

Each patient must be consulted well before the commencement of Ramadan and their risks stratified according to their unique circumstances.

Access to glucometers is an important aspect of fasting, as well as knowing who should and should not fast, how and when to test for glucose abnormalities and when to break the fast. A collaborative approach between patients living with diabetes, religious scholars and medical professionals is the ideal approach to ensure the safety of those who want to fast, and to assure those who should not fast that their religion most certainly permits that.

 


Reference:

  1. JEMDSA 2017 Volume 22 Number 1 (Supplement 1) Page 119-136

MEET OUR EXPERT


Dr Salim Parker is a general practitioner in Elsies River. He is an Honorary Research Associate: Department of Medicine, University of Cape Town and Immediate Past President: South African Society of Travel Medicine (SASTM).


Diabetes and fasting during Ramadan

With Ramadan approaching (26 May- 24 June), Diabetes Nurse Educator Razana Allie explains how having diabetes and fasting during Ramadan can be manageable.

The 26th of May is the start of most important month of the 2017 Muslim calendar. This month signifies and reaffirms our commitment to Islam and the five pillars which we conform to as Muslims. Islam is a way of life, and fasting is bestowed upon us as soon as we enter puberty until the time of death. As a Muslim, not fasting is a violation of who we are.

Sin, guilt, dishonesty and embarrassment are but a few words to describe what most feel when not fasting. The threat of developing complications or even death when fasting with an acute/chronic condition is not sufficient to deter most from fasting. This may result in complications which may have been prevented.

Diabetes is a chronic condition which, with education and support, can be managed to prevent complications and obtain a good quality of health.

During Ramadan, many factors influence the quality of our fasting day. Maintaining normal blood glucose while fasting is quite a challenge even to the person without diabetes.

Late nights with Taraweeh (Ramadan prayers) and early mornings with Suhur (pre-dawn meal) means less sleep. Waking early for Suhur to keep you nourished and satisfied until Iftar (breaking the fast) is a challenge.

Mild hypoglycaemia, dehydration, lethargy is the order of the day, to continue for 29 to 30 days of the month.

In South Africa, it’s business as usual. Very few companies acknowledge fasting and how difficult it is. Work life is the same as the other 11 months of the year. Expectations to perform continue, which is added pressure while fasting.

Possible complications while fasting may be:

Hypoglycaemia – While fasting there is no opportunity to correct the hypoglycaemia, which may lead to symptoms including confusion, irritability, coma or hospitalisation if witnessed. The liver provides glucose throughout the day until it becomes depleted of its stores.

Dehydration – may occur as fluid intake is only allowed at night and not during the day.

Thrombosis – the formation of blood clots. More prevalent with uncontrolled diabetes, cardiovascular disease, hypertension as well as dehydration.

Hyperglycaemia – may occur when medication is not taken to prevent hypoglycaemia while fasting.

Those who should not fast:

  • People with uncontrolled diabetes who use multiple doses of insulin, especially Type 1 diabetes.
  • Patients with long-term diabetes complications, such as kidney failure or heart disease.
  • Women with gestational diabetes.
  • Patients with a tendency of high blood glucose levels and those with high ketone levels.

ramadan_625x350_61465466111It is stated in the holy Quran, “Allah desires for you ease, and does not desire for you hardship.” – Ramadan Mubarak.

Can blood glucose levels be managed during Ramadan?

Diabetes can be manageable with education, guidance and support, provided you are low risk.

During pre-Ramadan, it is advisable to visit your doctor and diabetes educator to measure control and risk. This visit should also provide education on how to manage your blood glucose levels while fasting. Discussion on dosage reduction and target blood glucose for the month is important.

Management of hypoglycaemia as well as hyperglycaemia should be stressed and confirmed. Exercise is usually minimal during Ramadan, and most regard Salaah, during Taraweeh, as a form of exertion like exercise. However, parking far from the entrance at work or when shopping, and taking the stairs instead of the lift is manageable and acceptable forms of exertion.

Correct meal choices are important to get through the month of Ramadan. Minimal fats and carbohydrates, especially at Iftar, and additional proteins at Suhur is recommended. Faloodah with a sweetener instead of sugar; air fried or baked samosas instead of deep fried; two dates instead of six when breaking fast; baked curry balls instead of deep fried. Cake, biscuits, donuts and koeksisters may be taken in moderation at Iftar, provided you’re aware of the consequences of high blood glucose levels when consuming these foods.

In addition to the low GI carbohydrates, proteins are recommended at Suhur to provide and maintain energy levels throughout the day.

An increase in the intake of fluids at night is important; this will minimise dehydration throughout the day. Monitoring blood glucose is essential, with additional testing two hours after Suhur and Iftar, and before Asr Salaah for possible hyperglycaemia after meals and hypoglycaemia late afternoon. Changing injection times and adjusting insulin and oral dosages discussed with your doctor and diabetes educator before Ramadan prevents untoward abnormal blood glucose levels during the month.

Revisit your doctor and diabetes educator post Ramadan to readjust your medication and plan a way forward.

MEET OUR EXPERT - Rizana Allie

Razana Allie is a diabetes nurse educator.